

| Manned flight No. | 321 | 
| Manned flight of the Russia No. | 149 | 
| Manned flight Soyuz No. | 141 | 
| Launch: | Oct 14, 2020 05:45:04 | 
| Landing: | Apr 17, 2021 04:55:12 | 
| Duration: |  184 д 23 ч 10 м 8 с (4439 ч 10 м 8 с)  | 
				
| Orbits: | 2972 | 
| The proposed version of the Soyuz MS-17 crew up to Februar 20, 2020. | |

				Astronaut No. 545
Astronaut USA No. 336
Woman-astronaut No. 60
Rubins: 2nd flight
Cumulative time: 300 d 1 h 32 m 40 s
(7201 h 32 m 40 s)
Sergey Ryzhikov (Commander)
				Cosmonaut No. 548
Cosmonaut Russia No. 119
Ryzhikov: 2nd flight
Cumulative time: 358 d 2 h 25 m 15 s
(8594 h 25 m 15 s)
				Cosmonaut No. 564
Cosmonaut Russia No. 122
Kud-Sverchkov: 1st flight
Cumulative time: 184 d 23 h 10 m 8 s
(4439 h 10 m 8 s)
141st manned flight of the Soyuz. 61st flight of the Soyuz spacecraft to the ISS. Sergey Ryzhikov, Sergey Kud-Sverchkov and Kathleen Rubins joined Anatoly Ivanishin, Ivan Vagner and Christopher Cassidy in the 63rd crew of the ISS.

Crew befor the flight.

				Backup crew:
Mark Vande Hei, Oleg Novitskiy and Petr Dubov.

The crew arrived at the Baikonur cosmodrome.

Soyuz MS-17 is installed at the start.

Soyuz MS-17 approaches the ISS.

Crew inside the Kibo module.